{"id":3647,"date":"2024-01-22T22:52:12","date_gmt":"2024-01-22T22:52:12","guid":{"rendered":"https:\/\/www.ngdcare.nl\/product\/uncategorized\/nac-and-berberine\/"},"modified":"2026-11-05T22:23:17","modified_gmt":"2026-11-05T21:23:17","slug":"nac-and-berberine","status":"publish","type":"product","link":"https:\/\/www.ngdcare.nl\/en\/product\/veterinary-health\/search-by-complaints\/parasites-fleas-ticks\/nac-and-berberine\/","title":{"rendered":"Liposomal Metabolic Balance"},"content":{"rendered":"<div style=\"max-width: 860px; font-family: sans-serif; color: #333; line-height: 1.7;\">\n<div style=\"background: #eaf4ea; border-left: 4px solid #2b5040; padding: 18px 22px; margin-bottom: 28px;\">\n<p style=\"margin: 0; font-size: 1rem; color: #162920;\"><strong>QUICK SUMMARY<\/strong><\/p>\n<p style=\"margin: 0; font-size: 1rem; color: #162920;\">Metabolic Balance is a complementary feed for dogs and cats with 375 mg <span class=\"begrip-tooltip\" data-term=\"berberine\">berberine<span class=\"begrip-icon\" aria-hidden=\"true\">?<\/span><span class=\"begrip-popup\" aria-hidden=\"true\"><\/span><\/span> and 125 mg <span class=\"begrip-tooltip\" data-term=\"nac\">NAC<span class=\"begrip-icon\" aria-hidden=\"true\">?<\/span><span class=\"begrip-popup\" aria-hidden=\"true\"><\/span><\/span> per capsule. Metabolic Balance is formulated for normal metabolism. Use it in consultation with your vet.  <\/p>\n<\/div>\n<h2 style=\"font-size: 1.2rem; color: #2b5040; border-bottom: 2px solid #eaf4ea; padding-bottom: 8px; margin: 28px 0 16px;\">What&#8217;s in this supplement?<\/h2>\n<p>Each 500 mg capsule contains 375 mg berberine and 125 mg N-acetylcysteine (NAC). The capsule shell is made of HPMC and is therefore plant-based. The berberine has a liposomal component and a non-liposomal component, making it effective both inside and outside the intestines.  <\/p>\n<h2 style=\"font-size: 1.2rem; color: #2b5040; border-bottom: 2px solid #eaf4ea; padding-bottom: 8px; margin: 28px 0 16px;\">What does Metabolic Balance do?<\/h2>\n<p>Metabolic Balance is formulated for normal metabolism. It combines berberine with NAC, and should be used in consultation with your vet. <\/p>\n<h2 style=\"font-size: 1.2rem; color: #2b5040; border-bottom: 2px solid #eaf4ea; padding-bottom: 8px; margin: 28px 0 16px;\">The biochemistry per ingredient<\/h2>\n<h3 style=\"font-size: 1rem; color: #2b5040; margin: 18px 0 6px;\">Berberine<\/h3>\n<p>Berberine is a yellow plant substance from the <span class=\"begrip-tooltip\" data-term=\"alkaloiden\">alkaloid<span class=\"begrip-icon\" aria-hidden=\"true\">?<\/span><span class=\"begrip-popup\" aria-hidden=\"true\"><\/span><\/span> group. It is found in the barberry bush and yellow root, among others. Only a limited amount is absorbed in the gut, and the liver and gut bacteria convert it significantly. <\/p>\n<p>Research with cells and lab animals looks at the relationship with <span class=\"begrip-tooltip\" data-term=\"ampk\">AMPK<span class=\"begrip-icon\" aria-hidden=\"true\">?<\/span><span class=\"begrip-popup\" aria-hidden=\"true\"><\/span><\/span>. This is an <span class=\"begrip-tooltip\" data-term=\"enzym\">enzyme<span class=\"begrip-icon\" aria-hidden=\"true\">?<\/span><span class=\"begrip-popup\" aria-hidden=\"true\"><\/span><\/span> that acts as the cell&#8217;s energy sensor. Berberine can also affect the breakdown of certain medications.  <\/p>\n<h3 style=\"font-size: 1rem; color: #2b5040; margin: 18px 0 6px;\">NAC<\/h3>\n<p>NAC stands for N-acetylcysteine and is a source of cysteine, a building block of <span class=\"begrip-tooltip\" data-term=\"glutathion\">glutathione<span class=\"begrip-icon\" aria-hidden=\"true\">?<\/span><span class=\"begrip-popup\" aria-hidden=\"true\"><\/span><\/span>. The free sulfur group can break sulfur bridges in proteins.<\/p>\n<p style=\"background: #f7f5f0; padding: 12px 16px; font-size: .9rem;\"><strong>How strong is this evidence?<\/strong> Research on berberine comes from cell and animal trials and human studies. Less research has been conducted on dogs and cats. <\/p>\n<h2 style=\"font-size: 1.2rem; color: #2b5040; border-bottom: 2px solid #eaf4ea; padding-bottom: 8px; margin: 28px 0 16px;\">Frequently asked questions<\/h2>\n<div style=\"margin-bottom: 28px;\">\n<div style=\"background: #f9fcf9; border-left: 3px solid #d5cd47; padding: 14px 18px; margin-bottom: 10px;\">\n<h3 style=\"margin: 0 0 6px; font-size: .95rem; color: #162920;\">Why in consultation with the vet?<\/h3>\n<p style=\"margin: 0; font-size: .88rem; color: #555;\">Berberine can affect the breakdown of certain medications and is not suitable for every animal.<\/p>\n<\/div>\n<div style=\"background: #f9fcf9; border-left: 3px solid #d5cd47; padding: 14px 18px; margin-bottom: 10px;\">\n<h3 style=\"margin: 0 0 6px; font-size: .95rem; color: #162920;\">When should I not give Metabolic Balance?<\/h3>\n<p style=\"margin: 0; font-size: .88rem; color: #555;\">Do not give during pregnancy.<\/p>\n<\/div>\n<div style=\"background: #f9fcf9; border-left: 3px solid #d5cd47; padding: 14px 18px; margin-bottom: 10px;\">\n<h3 style=\"margin: 0 0 6px; font-size: .95rem; color: #162920;\">What are the possible side effects?<\/h3>\n<p style=\"margin: 0; font-size: .88rem; color: #555;\">In high amounts, NAC and berberine can cause nausea, vomiting, and altered stools.<\/p>\n<\/div>\n<\/div>\n<h2 style=\"font-size: 1.2rem; color: #2b5040; border-bottom: 2px solid #eaf4ea; padding-bottom: 8px; margin: 28px 0 16px;\">Why NGD Care Metabolic Balance?<\/h2>\n<div style=\"overflow-x: auto;\">\n<table style=\"width: 100%; border-collapse: collapse; font-size: .86rem;\">\n<thead>\n<tr style=\"background: #2b5040; color: #fff;\">\n<th style=\"padding: 11px 14px; text-align: left; font-weight: 600; width: 34%;\">Feature<\/th>\n<th style=\"padding: 11px 14px; text-align: left; font-weight: 600;\">NGD Care<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr style=\"background: #fff;\">\n<td style=\"padding: 10px 14px; border-bottom: 1px solid #eaf4ea; font-weight: 600;\">Form of administration<\/td>\n<td style=\"padding: 10px 14px; border-bottom: 1px solid #eaf4ea; color: #2b5040;\">A capsule that you can give whole or open and mix with food.<\/td>\n<\/tr>\n<tr style=\"background: #f9fcf9;\">\n<td style=\"padding: 10px 14px; border-bottom: 1px solid #eaf4ea; font-weight: 600;\">Human grade<\/td>\n<td style=\"padding: 10px 14px; border-bottom: 1px solid #eaf4ea; color: #2b5040;\">We use human-grade ingredients.<\/td>\n<\/tr>\n<tr style=\"background: #fff;\">\n<td style=\"padding: 10px 14px; border-bottom: 1px solid #eaf4ea; font-weight: 600;\">Clean and green label<\/td>\n<td style=\"padding: 10px 14px; border-bottom: 1px solid #eaf4ea; color: #2b5040;\">The capsule is free from synthetic additives.<\/td>\n<\/tr>\n<tr style=\"background: #f9fcf9;\">\n<td style=\"padding: 10px 14px; border-bottom: 1px solid #eaf4ea; font-weight: 600;\">Individual guidance<\/td>\n<td style=\"padding: 10px 14px; border-bottom: 1px solid #eaf4ea; color: #2b5040;\">Would you like personal advice for your animal? This is possible via a <a style=\"color: #2b5040;\" href=\"https:\/\/www.ngdcare.nl\/en\/consultation\/\">consultation with Stefan Veenstra<\/a>. <\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<div style=\"border: 1px solid #c8dbc8; padding: 20px 24px; margin: 28px 0;\">\n<p style=\"margin: 0 0 16px; font-size: .85rem; font-weight: bold; letter-spacing: .08em; text-transform: uppercase; color: #2b5040;\">Works well with<\/p>\n<div style=\"display: grid; grid-template-columns: repeat(auto-fit,minmax(240px,1fr)); gap: 12px;\">\n<div style=\"background: #f9fcf9; padding: 14px 16px; border-left: 3px solid #d5cd47;\">\n<p style=\"margin: 0 0 4px; font-weight: bold; color: #162920; font-size: .9rem;\"><a href=\"https:\/\/www.ngdcare.nl\/en\/product\/veterinary-health\/search-by-complaints\/cancer\/l-glutamine\/\">L-Glutamine<\/a><\/p>\n<p style=\"margin: 0; font-size: .83rem; color: #555;\"><span class=\"begrip-tooltip\" data-term=\"l-glutamine\">L-glutamine<span class=\"begrip-icon\" aria-hidden=\"true\">?<\/span><span class=\"begrip-popup\" aria-hidden=\"true\"><\/span><\/span> is a fuel for the cells of the intestinal wall.<\/p>\n<\/div>\n<div style=\"background: #f9fcf9; padding: 14px 16px; border-left: 3px solid #d5cd47;\">\n<p style=\"margin: 0 0 4px; font-weight: bold; color: #162920; font-size: .9rem;\"><a href=\"https:\/\/www.ngdcare.nl\/en\/product\/veterinary-health\/search-by-complaints\/cancer\/liposomal-glutathione\/\">Liposomal Glutathione<\/a><\/p>\n<p style=\"margin: 0; font-size: .83rem; color: #555;\">NAC is a source of cysteine. Liposomal Glutathione contains the tripeptide itself. <\/p>\n<\/div>\n<div style=\"background: #f9fcf9; padding: 14px 16px; border-left: 3px solid #d5cd47;\">\n<p style=\"margin: 0 0 4px; font-weight: bold; color: #162920; font-size: .9rem;\"><a href=\"https:\/\/www.ngdcare.nl\/en\/product\/veterinary-health\/search-by-supplements\/orthomolecular-supplements\/prebiotics\/\">Prebiotic Fibers<\/a><\/p>\n<p style=\"margin: 0; font-size: .83rem; color: #555;\">Prebiotic fibers serve as food for intestinal bacteria.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<div style=\"border: 1px solid #c8dbc8; padding: 18px 22px; margin: 28px 0; display: flex; align-items: center; justify-content: space-between; flex-wrap: wrap; gap: 12px;\">\n<div>\n<p style=\"margin: 0 0 4px; font-weight: bold; color: #2b5040; font-size: .95rem;\">Part of a protocol<\/p>\n<p style=\"margin: 0; color: #666; font-size: .88rem;\">Metabolic Balance is part of the Metabolic Balance Protocol. A protocol is a schedule in which multiple supplements are given in a fixed order. This protocol is intended for use in consultation with your vet.  <\/p>\n<\/div>\n<p><a style=\"display: inline-block; background: #2b5040; color: #fff; padding: 9px 20px; font-weight: bold; font-size: .85rem; text-decoration: none; white-space: nowrap; letter-spacing: .04em;\" href=\"https:\/\/www.ngdcare.nl\/en\/product\/veterinary-health\/search-by-supplements\/trajectories\/metabolic-support-bundle\/\">View the protocol<\/a><\/p>\n<\/div>\n<h2 style=\"font-size: 1.2rem; color: #2b5040; border-bottom: 2px solid #eaf4ea; padding-bottom: 8px; margin: 28px 0 16px;\">Scientific literature<\/h2>\n<ul style=\"padding-left: 20px; margin-bottom: 24px; font-size: .85rem; color: #555;\">\n<li style=\"margin-bottom: 6px;\">Tillhon M, et al. (2012). Berberine: new perspectives for old remedies. Biochemical Pharmacology.  <\/li>\n<li style=\"margin-bottom: 6px;\">Aldini G, et al. (2018). N-Acetylcysteine as an antioxidant and disulphide breaking agent: the reasons why. Free Radical Research.  <\/li>\n<\/ul>\n<div style=\"border: 1px solid #c8dbc8; padding: 18px 22px; margin: 28px 0; display: flex; align-items: center; justify-content: space-between; flex-wrap: wrap; gap: 12px;\">\n<div>\n<p style=\"margin: 0 0 4px; font-weight: bold; color: #2b5040; font-size: .95rem;\">Want to read more about nutrients and body processes?<\/p>\n<p style=\"margin: 0; color: #666; font-size: .88rem;\">In the knowledge base, you&#8217;ll find background articles on nutrition and how the body works. Do you have a question about this supplement or would you like personal advice? Please feel free to <a style=\"color: #2b5040;\" href=\"https:\/\/www.ngdcare.nl\/en\/contact\/\">contact us<\/a>.  <\/p>\n<\/div>\n<p><a style=\"display: inline-block; background: #2b5040; color: #fff; padding: 9px 20px; font-weight: bold; font-size: .85rem; text-decoration: none; white-space: nowrap; letter-spacing: .04em;\" href=\"https:\/\/www.ngdcare.nl\/en\/kennisbank\/\">To the knowledge base<\/a><\/p>\n<\/div>\n<div style=\"border-top: 2px solid #eaf4ea; padding-top: 20px; margin-top: 28px; display: flex; align-items: center; gap: 16px;\">\n<div style=\"background: #2b5040; color: #fff; width: 48px; height: 48px; border-radius: 50%; display: flex; align-items: center; justify-content: center; font-weight: bold; font-size: 1.1rem; flex-shrink: 0;\">SV<\/div>\n<p style=\"margin: 0; font-size: .88rem; color: #555;\">Developed by <strong style=\"color: #2b5040;\">Stefan Veenstra DVM<\/strong>, integrative veterinarian. Stefan is the founder of <a style=\"color: #2b5040;\" href=\"https:\/\/www.ngdcare.nl\/en\/\" target=\"_blank\" rel=\"noopener\">NGD Care<\/a>, <a style=\"color: #2b5040;\" href=\"https:\/\/www.ngdcareacademy.nl\" target=\"_blank\" rel=\"noopener\">NGD Care Academy<\/a> and <a style=\"color: #2b5040;\" href=\"https:\/\/www.natuurlijkgezondedieren.nl\" target=\"_blank\" rel=\"noopener\">Integrative Veterinary Center Natural Healthy Animals<\/a>. <a style=\"color: #2b5040;\" href=\"https:\/\/www.stefanveenstra.nl\" target=\"_blank\" rel=\"noopener\">Read more about Stefan \u2192<\/a> <\/p>\n<\/div>\n<p style=\"font-size: .78rem; color: #999; font-style: italic; margin-top: 24px; padding-top: 16px; border-top: 1px solid #eee;\">This information is educational in nature and does not replace a veterinary consultation. In case of severe or persistent complaints, always consult a veterinarian. <\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p style=\"font-weight: 400;\">NGD Care Metabolic Balance is a complementary feed for dogs and cats with 375 mg berberine and 125 mg N-acetylcysteine (NAC) per capsule. Metabolic Balance is formulated for normal metabolism. Use it in consultation with your vet.  <\/p>\n","protected":false},"featured_media":17761,"comment_status":"open","ping_status":"closed","template":"","meta":{"wds_primary_product_brand":0,"wds_primary_product_cat":17,"wds_primary_merken":0},"product_brand":[],"product_cat":[14603,192,14602,118,13872],"product_tag":[1031,139,1026,1362,1361,1359,272,1346,1028,1360],"merken":[],"class_list":["post-3647","product","type-product","status-publish","has-post-thumbnail","product_cat-parasites-fleas-ticks","product_cat-orthomolecular-supplements","product_cat-liver","product_cat-stomach-and-intestine","product_cat-metabolic-health","product_tag-biofilm-en","product_tag-cat","product_tag-giardia-en","product_tag-had-en","product_tag-intestinal-support","product_tag-n-acetyl-cysteine-en","product_tag-nac-en","product_tag-ngd-care-supplements","product_tag-parasites-en","product_tag-pathogens","infinite-scroll-item","sales-flash-overlay","woocommerce-text-align-center","woocommerce-image-align-center","do-quantity-buttons","first","instock","downloadable","taxable","shipping-taxable","purchasable","product-type-simple"],"meta_box":[],"_links":{"self":[{"href":"https:\/\/www.ngdcare.nl\/en\/wp-json\/wp\/v2\/product\/3647","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.ngdcare.nl\/en\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/www.ngdcare.nl\/en\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ngdcare.nl\/en\/wp-json\/wp\/v2\/comments?post=3647"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.ngdcare.nl\/en\/wp-json\/wp\/v2\/media\/17761"}],"wp:attachment":[{"href":"https:\/\/www.ngdcare.nl\/en\/wp-json\/wp\/v2\/media?parent=3647"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/www.ngdcare.nl\/en\/wp-json\/wp\/v2\/product_brand?post=3647"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/www.ngdcare.nl\/en\/wp-json\/wp\/v2\/product_cat?post=3647"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/www.ngdcare.nl\/en\/wp-json\/wp\/v2\/product_tag?post=3647"},{"taxonomy":"merken","embeddable":true,"href":"https:\/\/www.ngdcare.nl\/en\/wp-json\/wp\/v2\/merken?post=3647"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}