Longevity support
€ 49,95
NGD Care Longevity Support is a complementary feed for dogs and cats with NAD+, resveratrol, astragalus, and ergothioneine. This supplement is formulated to maintain healthy cells and tissues, also during aging.
- Contains NAD+, resveratrol, astragalus, and ergothioneine.
- The substances are in a liposomal form.
- You can also open the capsule and mix it with food.
- Intended for adult and senior animals.
- Description
- Ingredients
- Dosage and use
- Disclaimer
- Scientific literature & substantiation
- Reviews (1)
Description
QUICK SUMMARY
Longevity Support is a complementary feed for dogs and cats with NAD+, resveratrol, astragalus, and ergothioneine. This supplement is formulated to maintain healthy cells and tissues.
What’s in this supplement?
Each 450 mg capsule contains 100 mg NAD+ (nicotinamide adenine dinucleotide), 75 mg resveratrol, 30 mg astragalus, and 5 mg ergothioneine. Excipients are sunflower lecithin and gum arabic. The capsule shell is made of HPMC and is therefore plant-based.
What does Longevity Support do?
Longevity Support is formulated to maintain healthy cells and tissues. The name refers to the field of research, and there is no evidence that these substances extend life.
The biochemistry per ingredient
NAD+
NAD+ is a cofactor in cellular energy production. Enzymes such as sirtuins and PARPs also use it. In humans and laboratory animals, levels in tissues can decrease with age. NAD+ itself is poorly absorbed via the gut, and it is unknown how much reaches the cell. This is the reason for the liposomal processing to increase bioavailability.
Resveratrol
Resveratrol is a polyphenol found in grape skins, among other things. It is well absorbed but then rapidly metabolized, so little of the unchanged substance remains in the blood.
Ergothioneine
Ergothioneine is a sulfur-containing amino acid from mushrooms. The body does not produce it itself but has its own transport protein for it.
Astragalus
Astragalus is a leguminous plant containing saponins, sugar chains, and flavonoids.. Research mainly focuses on cells and laboratory animals.
How strong is this evidence? The role of NAD+ in metabolism is well established, but NAD+ itself is poorly absorbed via the gut. Research into resveratrol, astragalus, and ergothioneine comes mainly from trials with cells and animals. There is no evidence that these substances extend the life of dogs or cats.
Frequently asked questions
From what age can I give Longevity Support?
Longevity Support is intended for adult and senior animals. If in doubt, consult your veterinarian.
Does Longevity Support extend life?
There is no evidence for that. The name refers to the field of research, not to a proven effect.
What are the possible side effects?
Nausea and changed stools may occur at the start or with high amounts.
Why NGD Care Longevity Support?
| Feature | NGD Care |
|---|---|
| Administration form | A vegetable capsule with liposomal content. You can give it whole or open it and mix it through the food. |
| Human grade | We use human-grade ingredients. |
| Clean and green label | The capsule is free from synthetic additives. |
| Individual guidance | Would you like personal advice for your animal? This is possible via a consultation with Stefan Veenstra. |
Works well with
NADH supplies electrons to the chain in which coenzyme Q10 works.
Glutathione is the most important antioxidant within the cell.
Shilajit contains dibenzo-alpha-pyrones, which are being researched in relation to the mitochondria.
Part of a protocol
Longevity Support is part of the Senior Support Protocol. A protocol is a schedule in which multiple supplements are given in a fixed order.
Scientific literature
- Covarrubias AJ, et al. (2021). NAD+ metabolism and its roles in cellular processes during ageing. Nature Reviews Molecular Cell Biology.
- Walle T. (2011). Bioavailability of resveratrol. Annals of the New York Academy of Sciences.
- Cheah IK, Halliwell B. (2012). Ergothioneine; antioxidant potential, physiological function and role in disease. Biochimica et Biophysica Acta.
- Fu J, et al. (2014). Review of the botanical characteristics, phytochemistry, and pharmacology of Astragalus membranaceus (Huangqi). Phytotherapy Research.
Want to read more about nutrients and body processes?
In the knowledge base, you’ll find background articles on nutrition and how the body works. Do you have a question about this supplement or would you like personal advice? Please feel free to contact us.
Developed by Stefan Veenstra DVM, integrative veterinarian. Stefan is the founder of NGD Care, NGD Care Academy and Integrative Veterinary Center Natural Healthy Animals. Read more about Stefan →
This information is educational in nature and does not replace a veterinary consultation. In case of severe or persistent complaints, always consult a veterinarian.
Ingredients
- Ingredients
- NAD (Nicotinamide Adenine Dinucleotide), resveratrol, astragalus, ergothioneine
- Composition per 450mg capsule
- 100mg NAD+
- 75 mg Resveratrol
- 30 mg Astragalus
- 5 mg Ergothioneine
- Additions
- Lipodry liposome: sunflower lecithin
- Rice starch
- HMPC vega capsule
Dosage and use
- Dosage dog and cat
- Starting dosage
- on the advice of a veterinarian or therapist
- <10kg 2xdaily 1/2 capsule
- 10-30kg 1 capsule 2xdaily
- >30kg 2x daily 2 capsules
- Maintenance Dosing
- <10kg 1x daily 1/2 capsule
- 10-30kg 1x daily 1 capsule
- >30kg 2 capsules 1x day
- Starting dosage
- Manual
- Capsules can be administered opened or whole through food.
- Store in a dry, sealed and room temperature.
- Contraindications
- Haven’t been found yet.
- Side effects
- Possibly: nausea, diarrhea, fatigue or headache, especially at start-up or high dose
- Interactions
- Resveratrol can inhibit CYP1A2
Disclaimer
- This product is a dietary supplement and not a substitute for a healthy lifestyle and varied balanced diet.
- The products are not medicines and cannot be used as medicines, but as a dietary supplement. In case of illness or other medical condition, always consult a veterinarian before use.
- Dietary supplements may have interactions and side effects with regular medications.
- Keep out of reach of young children.
- Consult an expert before using supplements in case of pregnancy, lactation, medication use and illness.
Scientific literature & substantiation
- NAD and Cell Aging
- NAD levels decline with age and are crucial for DNA repair, sirtuin activation, and energy metabolism.
- Source: Verdin, E. (2015). NAD+ in aging, metabolism, and neurodegeneration. Science
- Liposomal delivery increases availability of NAD
- Liposomes protect against gastric acid breakdown and promote cellular absorption.
- Source: Harrison, K., et al. (2020). Liposomal delivery enhances NAD+ bioavailability in humans. Nutrients
- Resveratrol and sirtuin activation
- Resveratrol activates sirtuin-1, slows down aging and supports metabolism.
- Source: Baur, J. A., & Sinclair, D. A. (2006). Therapeutic potential of resveratrol: the in vivo evidence. Nature Reviews Drug Discovery
- Ergothioneine as a neuroprotective antioxidant
- Ergothioneine accumulates in brain and vital organs and provides protection against oxidative damage.
- Source: Cheah, I. K., & Halliwell, B. (2012). Ergothioneine; antioxidant potential, physiological function and role in disease. Biochimica et Biophysica Acta
- Ergothioneine and cardiovascular/metabolic health
- Lower blood levels of ergothioneine are associated with increased risk of cardiovascular and metabolic disease.
- Source: Smith, E., et al. (2020). Ergothioneine is associated with reduced mortality and decreased cardiovascular risk. Free Radical Biology and Medicine
1 review for Longevity support
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Monique ten Hagen (verified owner) –
I have been seeing and noticing the effects since my dog has been using this product. She recently turned 15 and is still vital for her age.
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Ik zie en merk de effecten sinds mijn hond dit product gebruikt. Ze is onlangs 15 jaar geworden en nog steeds vitaal voor haar leeftijd.
Stefan –
Thank you for your response.
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Dank je wel voor je reactie.
Stefan –
Thank you for your response. On to 16!
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Dank je wel voor je reactie. Op naar de 16!