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Scientifically proven ingredients

Liposomal Metabolic Balance

€ 44,95

NGD Care Metabolic Balance is a complementary feed for dogs and cats with 375 mg berberine and 125 mg N-acetylcysteine (NAC) per capsule. Metabolic Balance is formulated for normal metabolism. Use it in consultation with your vet.

  • Each capsule contains a portion of liposomal and a portion of regular berberine and NAC.
  • Berberine is a yellow plant substance found in the barberry bush, among others.
  • You can also open the capsule and mix it with food.
  • Use Metabolic Balance in consultation with your vet.

Description

QUICK SUMMARY

Metabolic Balance is a complementary feed for dogs and cats with 375 mg berberine and 125 mg NAC per capsule. Metabolic Balance is formulated for normal metabolism. Use it in consultation with your vet.

What’s in this supplement?

Each 500 mg capsule contains 375 mg berberine and 125 mg N-acetylcysteine (NAC). The capsule shell is made of HPMC and is therefore plant-based. The berberine has a liposomal component and a non-liposomal component, making it effective both inside and outside the intestines.

What does Metabolic Balance do?

Metabolic Balance is formulated for normal metabolism. It combines berberine with NAC, and should be used in consultation with your vet.

The biochemistry per ingredient

Berberine

Berberine is a yellow plant substance from the alkaloid group. It is found in the barberry bush and yellow root, among others. Only a limited amount is absorbed in the gut, and the liver and gut bacteria convert it significantly.

Research with cells and lab animals looks at the relationship with AMPK. This is an enzyme that acts as the cell’s energy sensor. Berberine can also affect the breakdown of certain medications.

NAC

NAC stands for N-acetylcysteine and is a source of cysteine, a building block of glutathione. The free sulfur group can break sulfur bridges in proteins.

How strong is this evidence? Research on berberine comes from cell and animal trials and human studies. Less research has been conducted on dogs and cats.

Frequently asked questions

Why in consultation with the vet?

Berberine can affect the breakdown of certain medications and is not suitable for every animal.

When should I not give Metabolic Balance?

Do not give during pregnancy.

What are the possible side effects?

In high amounts, NAC and berberine can cause nausea, vomiting, and altered stools.

Why NGD Care Metabolic Balance?

Feature NGD Care
Form of administration A capsule that you can give whole or open and mix with food.
Human grade We use human-grade ingredients.
Clean and green label The capsule is free from synthetic additives.
Individual guidance Would you like personal advice for your animal? This is possible via a consultation with Stefan Veenstra.

Works well with

L-Glutamine

L-glutamine is a fuel for the cells of the intestinal wall.

Liposomal Glutathione

NAC is a source of cysteine. Liposomal Glutathione contains the tripeptide itself.

Prebiotic Fibers

Prebiotic fibers serve as food for intestinal bacteria.

Part of a protocol

Metabolic Balance is part of the Metabolic Balance Protocol. A protocol is a schedule in which multiple supplements are given in a fixed order. This protocol is intended for use in consultation with your vet.

View the protocol

Scientific literature

  • Tillhon M, et al. (2012). Berberine: new perspectives for old remedies. Biochemical Pharmacology.
  • Aldini G, et al. (2018). N-Acetylcysteine as an antioxidant and disulphide breaking agent: the reasons why. Free Radical Research.

Want to read more about nutrients and body processes?

In the knowledge base, you’ll find background articles on nutrition and how the body works. Do you have a question about this supplement or would you like personal advice? Please feel free to contact us.

To the knowledge base

SV

Developed by Stefan Veenstra DVM, integrative veterinarian. Stefan is the founder of NGD Care, NGD Care Academy and Integrative Veterinary Center Natural Healthy Animals. Read more about Stefan →

This information is educational in nature and does not replace a veterinary consultation. In case of severe or persistent complaints, always consult a veterinarian.

Ingredients

  • Ingredients
    • NAC, Berberine
  • Composition per capsule of 500mg
    • 125mg NAC
    • 375mg Berberine
      • of which 75mg liposomal berberine
  • Additions
    • Lipodry liposome: sunflower lecithin
    • HMPC vega capsule

Dosage and use

  • Dosage dog and cat
    • Starting dosage
      • on the advice of a veterinarian or therapist
      • <10kg 2xdaily 1/2 capsule
      • 10-30kg 1 capsule 2xdaily
      • >30kg 2x daily 2 capsules
    • Maintenance Dosing
      • <10kg 1x daily 1/2 capsule
      • 10-30kg 1x daily 1 capsule
      • >30kg 1xdags 2 capsules
  • Manual
    • Capsules can be administered opened or whole through food.
    • Store in a dry, sealed and room temperature.
  • Contraindications
    • in case of pregnancy
  • Side effects
    • NAC and berberine can lead to nausea, vomiting, diarrhea and constipation in high doses.
  • Interactions
    • Berberine inhibits the enzyme CYP3A4, an enzyme that metabolizes many drugs. Berberine can slow down the breakdown of these medications. Mainly with tetracyclines, statins and blood sugar-lowering medication.

Disclaimer

  • This product is a dietary supplement and not a substitute for a healthy lifestyle and varied balanced diet.
  • The products are not medicines and cannot be used as medicines, but as a dietary supplement. In case of illness or other medical condition, always consult a veterinarian before use.
  • Dietary supplements may have interactions and side effects with regular medications.
  • Keep out of reach of young children.
  • Consult an expert before using supplements in case of pregnancy, lactation, medication use and illness.

Scientific literature & substantiation

  1. NAC and biofilm degradation in Candida
    • NAC disrupts the structure of biofilms and enhances the action of antifungal drugs.
    • Source: Aslam, S., et al. (2007). N-acetylcysteine as an adjuvant to antibiotics against biofilm-producing Pseudomonas aeruginosa. Journal of Antimicrobial Chemotherapy,
  2. NAC in Giardia and detoxification
    • NAC helps in the breakdown of Giardia biofilm and supports liver function and antioxidant status.
    • Source: Queirós, S. C., et al. (2022). N-Acetylcysteine as a potential antiparasitic drug: Mechanisms and uses. Pharmaceuticals
  3. Berberine as a broad antimicrobial agent
    • Berberine works against a wide range of pathogens including parasites, yeasts and bacteria.
    • Source: Tillhon, M., et al. (2012). Berberine: new perspectives for old remedies. Biochemical Pharmacology
  4. Berberine and microbiome repair
    • Berberine prevents disbiosis and supports the intestinal epithelium.
    • Source: Habtemariam, S. (2020). Berberine pharmacology and the gut microbiota: A hidden therapeutic link. Pharmacological Research
  5. Combination use with regular therapy
    • Berberine works synergistically with antifungal and antiparasitic agents.
    • Source: Mahady, G. B., et al. (2002). In vitro susceptibility of Helicobacter pylori to botanical extracts used traditionally for the treatment of gastrointestinal disorders. Phytotherapy Research

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Liposomal Metabolic Balance
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