Liposomal PEA complex
€ 47,95
NGD Care PEA Complex is a complementary feed for dogs and cats with 150 mg palmitoylethanolamide (PEA) and 150 mg Boswellia serrata per capsule, in liposomal form. PEA is a fatty acid amide that the body also produces itself. Boswellia is a gum resin from the frankincense tree. This complex is formulated for flexible joints.
- Natural support for chronic pain, inflammation and osteoarthritis
- Helps with nerve pain, glaucoma, arthritis and intestinal complaints
- Has an anti-inflammatory and neuroprotective effect
- Liposomal delivery for better absorption
- Safe alternative or supplement to regular medication
- Description
- Ingredients
- Dosage and use
- Disclaimer
- Scientific literature & substantiation
- Reviews (0)
Description
QUICK SUMMARY
PEA Complex is a complementary feed for dogs and cats with 150 mg palmitoylethanolamide (PEA) and 150 mg Boswellia serrata per capsule, in liposomal form. This complex is formulated for flexible joints.
What’s in this supplement?
Each 400 mg capsule contains 150 mg palmitoylethanolamide (PEA) and 150 mg Boswellia serrata. Both substances are encapsulated by liposomes: small fat bubbles made of sunflower lecithin. The capsule shell is made of HPMC and is therefore plant-based.
The biochemistry of PEA and Boswellia
PEA. PEA is a fatty substance that the body produces itself. It acts as a messenger between cells.
How PEA works. PEA fits into a kind of lock in the cell called PPAR-alpha. Through that lock, the cell receives a signal about which proteins it needs to produce.
Boswellia. Boswellia is the resin of the frankincense tree. The active substances are called boswellic acids and dissolve in fat.
Two routes. Boswellic acids are studied in relation to the enzyme 5-LOX. An enzyme is a protein that allows a reaction to take place in the body. PEA works via a different route, so the two substances complement each other.
How strong is this evidence? The biochemistry of PEA mainly comes from tests with cells and animals. Boswellic acids act strongly on 5-LOX in the laboratory, but in blood, the results are less clear. What this means for dogs and cats at the dosage used does not follow from this.
What does this supplement do?
- PEA and Boswellia serrata are combined for flexible joints.
- PEA and Boswellia serrata are intended for maintaining flexible joints, even as animals age.
- The liposomal form was chosen to support the absorption of these fat-soluble substances.
How to use this supplement
For the first 4 to 8 weeks, give 2x daily: under 10 kg ½ capsule, from 10 to 30 kg 1 capsule, and over 30 kg 2 capsules.
After that, give the same amount once daily. You can continue this for a longer period.
Give the capsule whole or open it and mix the contents into the food.
Boswellia can influence the breakdown of some medications. Consult your vet first if your pet is on medication.
Frequently asked questions
What is PEA?
PEA stands for palmitoylethanolamide. It is a fatty acid amide that the body produces itself and is also found in foods such as egg yolks and peanuts.
What is the difference between PEA and CBD?
PEA is a lipid that the body produces itself and that binds to PPAR-alpha. CBD is a cannabinoid from hemp. Both substances are studied within the endocannabinoid system.
Why does PEA Complex also contain Boswellia?
PEA and boswellic acids are different substances with their own biochemical route. PEA binds to PPAR-alpha. Boswellic acids are studied in relation to 5-LOX. That is why they are together in one capsule.
Why a liposomal form?
PEA and boswellic acids dissolve poorly in water. Liposomes are small fat bubbles that encapsulate these substances. We choose this form to support absorption.
My pet is on medication. Can I still use PEA Complex?
Consult your vet first. Boswellia can influence cytochrome P450, an enzyme system that breaks down many medications, as well as blood glucose levels.
Why NGD Care PEA Complex?
| Feature | NGD Care |
|---|---|
| Administration form | Capsule with PEA, Boswellia serrata, sunflower lecithin, and an HPMC shell. |
| Human grade | We use human-grade ingredients. |
| Clean and green label | The capsule is free from synthetic additives. |
| Developed by | Stefan Veenstra, integrative veterinarian and founder of NGD Care. |
| Individual guidance | Would you like personal advice for your animal? This is possible via a consultation with Stefan Veenstra. |
Works well with
Mobility Support contains building blocks for cartilage, such as glucosamine and chondroitin sulfate. PEA Complex is formulated for flexible joints. In this way, the two products complement each other.
O-Mega Blend contains omega-3 fatty acids, which, like PEA, belong to the lipids. Omega-3 fatty acids are incorporated into cell membranes, from which the body also produces PEA.
Curcumin is a polyphenol from turmeric and, like PEA and boswellic acids, is fat-soluble. Curcumin is studied within different signaling pathways than PEA.
CBD is a cannabinoid from hemp and PEA is a body-own lipid. Both substances are studied within the endocannabinoid system, via different routes.
Part of a protocol
PEA Complex is part of the Joint Support Protocol. A protocol is a schedule in which multiple supplements are given in a fixed order.
Scientific literature
- Okamoto Y, et al. (2004). Molecular characterization of a phospholipase D generating anandamide and its congeners. Journal of Biological Chemistry.
- Tsuboi K, et al. (2005). Molecular characterization of N-acylethanolamine-hydrolyzing acid amidase. Journal of Biological Chemistry.
- O’Sullivan SE. (2016). An update on PPAR activation by cannabinoids. British Journal of Pharmacology.
- Büchele B, et al. (2003). Analysis of pentacyclic triterpenic acids from frankincense gum resins and related phytopharmaceuticals by high-performance liquid chromatography. Journal of Chromatography B.
- Abdel-Tawab M, et al. (2011). Boswellia serrata: an overall assessment of in vitro, preclinical, pharmacokinetic and clinical data. Clinical Pharmacokinetics.
Want to read more about nutrients and body processes?
In the knowledge base, you will find background articles about nutrition and how the body works.
This information is educational in nature and does not replace a veterinary consultation. In case of severe or persistent complaints, always consult a veterinarian.
Ingredients
- Ingredients
- Palmitoylethanolamide, Boswellia Serrata
- Composition per capsule of 400mg
- 150mg Boswellia serrata
- 150mg Palmitoylethanolamide (PEA)
- Additions
- Lipodry liposome: sunflower lecithin
- HPMC vega capsule
Dosage and use
- Dosage dog and cat
- Therapeutic dosage
- on the advice of a veterinarian or therapist
- <10kg 2xdaily 1/2 capsule
- 10-30kg 1 capsule 2xdaily
- >30kg 2x daily 2 capsules
- Maintenance Dosing
- <10kg 1x daily 1/2 capsule
- 10-30kg 1x daily 1 capsule
- >30kg 2 capsules 1x day
- Therapeutic dosage
- Manual
- Capsules can be administered opened or whole through food.
- Store in a dry, sealed and room temperature.
- Capsules can be administered opened or whole through food.
- Contraindications
- no known contraindications
- Side effects
- Upset stomach, diarrhea, skin reactions, and headaches have rarely been observed.
- Interactions
- Boswellia can affect blood glucose levels
- Boswellia inhibits Cytochrome P450, which can slow the breakdown of NSAIDs, blood thinners, and diabetes medications.
Disclaimer
- This product is a dietary supplement and not a substitute for a healthy lifestyle and varied balanced diet.
- The products are not medicines and cannot be used as medicines, but as a dietary supplement. In case of illness or other medical condition, always consult a veterinarian before use.
- Dietary supplements may have interactions and side effects with regular medications.
- Keep out of reach of young children.
- Consult an expert before using supplements in case of pregnancy, lactation, medication use and illness.
Scientific literature & substantiation
- PEA for pain and inflammation
- PEA has anti-inflammatory, analgesic, and neuroprotective properties.
- Source: Keppel Hesselink, J. M., et al. (2013). Palmitoylethanolamide, a natural neuroprotective agent in nerve compression syndromes. Pain Physician
- PEA for glaucoma
- PEA lowers intraocular pressure and protects retinal cells.
- Source: Bucolo, C., et al. (2011). Palmitoylethanolamide reduces intraocular pressure and protects the retina in a glaucoma model. Journal of Cellular and Molecular Medicine
- Boswellia for inflammation and pain
- Boswellia extract reduces joint pain and inflammatory markers in chronic conditions.
- Source: Sengupta, K., et al. (2008). A double blind, randomized, placebo controlled study of the efficacy and safety of 5-Loxin for treatment of osteoarthritis of the knee. Arthritis Research & Therapy
- Synergistic effect PEA + Boswellia
- Combination inhibits pain and inflammatory pathways on multiple levels.
- Source: Impellizzeri, D., et al. (2014). Palmitoylethanolamide and Boswellia serrata: a new possible treatment for chronic pain. European Review for Medical and Pharmacological Sciences
- Boswellia and medication interactions
- Boswellia affects cytochrome P450 and glucose management.
- Source: Sharma, M. L., & Bani, S. (1990). Boswellic acids: anti-inflammatory and immunomodulatory agents. Planta Medica
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